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According to recent research from Colombes, France, " Relationships between pain threshold during rectal distension and both symptoms intensity and alteration in quality of life (QoL) in irritable bowel syndrome (IBS) patients have been poorly evaluated. To evaluate relationships between rectal sensitivity, IBS symptom intensity and QoL in a multicentre prospective study."
" Rectal threshold for moderate pain was measured during rectal distension in IBS patients (Rome 11), while IBS symptoms intensity was assessed by a validated questionnaire and QoL by the Functional Digestive Disorder Quality of Life questionnaire. Sixty-eight patients (44.2 +/- 12.7 years, 48 women) were included. The mean rectal distending volume for moderate pain was 127 35 mL while 45 patients (66%) had rectal hypersensitivity (pain threshold
The researchers concluded: "No significant correlation was found between rectal threshold and C, either symptom intensity or alteration in QoL."
Sabate and colleagues published their study in Alimentary Pharmacology & Therapeutics (Relationship between rectal sensitivity, symptoms intensity and quality of life in patients with irritable bowel syndrome. Alimentary Pharmacology & Therapeutics, ...
Source: HighBeam Research, Studies from J.M. Sabate et al have provided new data on irritable...