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City University of New York, Medical Department reports research in Down syndrome.
According to recent research published in the journal Neurobiology of Aging, "We investigated synaptic plasticity in persons with Down' syndrome (DS) and control subjects used paired associative stimulation (PAS) protocol, a paradigm capable of producing long-term potentiation (LTP)-like changes in the sensorimotor system."
"After PAS, patients showed less LTP-like plasticity compared to control subjects," wrote F. Battaglia and colleagues, City University of New York, Medical Department (see also Down Syndrome).
The researchers concluded: "Abnormal motor cortex synaptic plasticity may play a role in the development of motor signs in DS."
Battaglia and colleagues published their study in Neurobiology of Aging (Early impairment of synaptic plasticity in patients with Down's syndrome. Neurobiology of Aging, ...
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Source: HighBeam Research, City University of New York, Medical Department reports research in...