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New cardiology research from University of Leuven discussed.
"Strain and strain rate (SR) are measures of deformation that reflect left ventricular (LV) function. To our knowledge, no previous study described these indexes in a general population," investigators in Louvain, Belgium report (see also Cardiology).
"We therefore described peak-systolic strain and SR of the LV in the general population and derived diagnostic thresholds for these measurements in a healthy subgroup. In 480 subjects enrolled in a family-based population study (50.5% women; mean age, 50.5 years; 37.2% hypertensive), we measured: (i) end-systolic longitudinal strain and peak-systolic SR from the basal portion of the LV inferior and inferolateral free walls; (ii) radial deformation of the LV inferolateral wall. Longitudinal (mean, 22.9%) and radial (59.2%) strain and longitudinal (1.31 s(-1)) and radial (3.40 s(-1)) SR decreased with age (P
The researchers concluded: "Our current study resulted in the proposal for diagnostic thresholds for strain and SR, based on a healthy subgroup recruited via random sampling of the population."
Kuznetsova and colleagues published their study in European Heart Journal (Left ventricular strain and strain rate in a general population. European Heart Journal, 2008;29(16):2014-2023).
For additional information, contact J.A. Staessen, Catholic University of Leuven, ...
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Source: HighBeam Research, New cardiology research from University of Leuven discussed.