Research from A. Alberichbayarri and co-researchers in the area of bone research described.(Report)

According to recent research published in the American Journal of Roentgenology, "The purpose of this study was to investigate the in vivo morphologic and elastic parameters of trabecular bone with high-resolution 3-T MRI in a healthy reference population. A series of wrist MR images were acquired with high-spatialresolution (180 mu m) isotropic voxels from 40 subjects without reported bone disease."

"After image postprocessing, the bone volume-to-total volume ratio, trabecular thickness, trabecular separation, and trabecular number were calculated in the morphologic analysis. Trabecular bone was mechanically simulated using the finite-element method to calculate the apparent elastic modulus parameter. The relationship between morphologic and mechanical parameters was studied. The influence of the analyzed bone volume was also investigated. Statistically significant sex influences were found on the bone volume-to-total volume ratio (p = 0.003), trabecular thickness (p = 0.02), and apparent elastic modulus (p = 0.01); these parameters were lower in women. However, trends were found only on trabecular separation (p = 0.06) and trabecular number (p = 0.07). Age had no statistically significant influence in any morphologic (bone volume-to-total volume ratio, r = -0.24, p = 0.13; trabecular thickness, r = -0.03, p = 0.88; trabecular separation, r = 0.12, p = 0.47; and trabecular number, r = -0.23, p = 0.16) or elastic (apparent elastic modulus, r = -0.18, p = 0.26) parameter. A statistically significant relationship between ...