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New Alzheimer disease findings from T.A. Ishunina and co-authors described.
According to a study from Netherlands, "A role of estrogens in brain aging and Alzheimer's disease (AD) is a hot topic of research. We show in material of 71 patients that the estrogen receptor alpha (ER alpha.) splice variant MB1 is expressed at the protein and mRNA level in the human brain."
"MB1 is mainly confined to astrocytes, membranes and cytoplasm of projecting neurons and endothelial cells. It was consistently observed in the thalamus, colliculus inferior, pontine nuclei, dorsal motor nucleus of vagus,'some motor neurons in the anterior and lateral horns of the spinal cord and rarely in pyramidal neurons of the cerebral cortex. The highest level of MB1 immunoreactivity (MB1-ir) was noted in the caudal hypothalamus, in particular in the tuberomamillary nucleus (TMN). MB1-ir in the TMN increased during aging in women. MB1-ir was higher in young (
The researchers concluded: "NIB I may function as a dominant negative isoform in the human brain."
Ishunina and colleagues published the results of their research in Neurobiology of ...
- HSPG2 A, APOE epsilon 4 alleles combined increase risk for Alzheimer disease.
- Newspaper article from: Mental Health Weekly Digest January 19, 2004 700+ words
...creates high risk for Alzheimer disease. "A genetic association...2 (HSPG2) with Alzheimer disease (AD) was investigated...Health, Risk Factor, Alzheimer Disease, Proteomics, and...prepared by Mental Health Weekly Digest editors from...
- Researchers from University of Missouri, Department of Chemistry report details...
- Magazine article from: Women's Health Weekly April 9, 2009 700+ words
...Chemistry (see also Alzheimer Disease). The researchers...States, Columbia, Alzheimer Disease, Mass Spectrometry...prepared by Women's Health Weekly editors from staff...2009, Women's Health Weekly via NewsRx.com...
- A-beta antibody levels not changed in patients with Alzheimer disease.
- Newspaper article from: Mental Health Weekly Digest March 29, 2004 700+ words
...36 patients with Alzheimer disease (AD) and 34 age...respond to potential Alzheimer disease immune therapy...subject areas of Alzheimer Disease, Immunology, Cognition...prepared by Mental Health Weekly Digest editors from...
- Reports from University of Belgrade describe recent advances in Alzheimer...
- Magazine article from: Women's Health Weekly October 30, 2008 700+ words
...individuals suffering from Alzheimer disease (AD)." "The...Belgrade (see also Alzheimer Disease). The researchers...Serbia, Aging, Alzheimer Disease, Neurochemistry...prepared by Women's Health Weekly editors from staff...
- Research from S. Knafo and co-researchers in the area of Alzheimer disease...
- Newspaper article from: Mental Health Weekly Digest February 23, 2009 700+ words
...colleagues, (see also Alzheimer Disease). The researchers...Spain, Madrid, Alzheimer Disease, Central Nervous...prepared by Mental Health Weekly Digest editors from...Copyright 2009, Mental Health Weekly Digest via NewsRx...
- Data on Alzheimer disease described by researchers at Nagoya City University.
- Newspaper article from: Mental Health Weekly Digest January 26, 2009 700+ words
...Alzheimer Disease. Alzheimer Disease & Associated...information for the journal Alzheimer Disease & Associated...Japan, Nagoya, Alzheimer Disease, Depression, Mental...prepared by Mental Health Weekly Digest editors from...
- Physiological role of beta-amyloid peptide explains Alzheimer disease.
- Newspaper article from: Mental Health Weekly Digest March 29, 2004 700+ words
...the pathogenesis of Alzheimer disease. In a recent study...neuropathology of Alzheimer disease," wrote Jose A...subject areas of Alzheimer Disease, Cognition, Geriatrics...prepared by Mental Health Weekly Digest editors from...
- New Alzheimer disease study findings reported from University of Sydney.(Report)
- Newspaper article from: Mental Health Weekly Digest September 28, 2009 700+ words
...Sydney (see also Alzheimer Disease). The researchers...Keywords: Australia, Alzheimer Disease, Biochemical, Central...prepared by Mental Health Weekly Digest editors from...Copyright 2009, Mental Health Weekly Digest via NewsRx...