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New clinical trial research research has been reported by J. Rosenthal et al.
"Observational studies and clinical trials have shown conclusive evidence that periconceptional folic acid supplementation prevents up to 70% of neural tube defects (NTD). The Honduran government wanted to implement a Supplementation programme of folic acid but needed to assess the relative effects of two dosages of folic acid," scientists in the United States report (see also Clinical Trial Research).
"To determine the effect of two dosages of folic acid on blood folate levels in Honduran female factory workers aged 18 to 49 years. This was a randomized, double-blind control supplementation trial conducted in Choloma, Honduras. A total of 140 eligible women were randomly assigned to two dosage groups and followed Lip for 12 weeks. One group received a daily dosage of 1 mg folic acid and the other a once weekly dosage of 5 mg. Serum folate and red blood cell folate levels were determined by radioassay at baseline, 6 weeks and 12 weeks. Serum folate levels increased from 6.3 (SE 0.2) to 14.9 (SE 0.6) ng/ml (P
The researchers concluded: "Although both folate supplementation regimens increased serum and red blood cell folate levels significantly among the women studied, blood folate levels that are considered to be protective of NTD were reached faster with the daily dosage of 1 mg folic acid."
Rosenthal and colleagues published their study in Public Health Nutrition (Effect of different ...
- Folate levels decline in women; impact unknown.(Women's Health)
- Magazine article from: Internal Medicine News Schneider, Mary Ellen February 1, 2007 700+ words
...surveys. Trends in red blood cell folate levels from the 1999-2000 through 2003...becoming pregnant consume 400 mcg of folic acid daily to reduce the chance of neural...reason behind the reported drop in folate levels is unknown, but the researchers...
- Folate levels decrease in nonpregnant women.(Clinical Rounds)
- Magazine article from: Skin & Allergy News Schneider, Mary Ellen March 1, 2007 700+ words
...surveys. Trends in red blood cell folate levels from the 1999-2000 through 2003...becoming pregnant consume 400 mcg of folic acid daily to reduce the chance of neural...reason behind the reported drop in folate levels is unknown, but the researchers...
- Folate levels decline in women; impact unknown.(News)(Survey)
- Magazine article from: Family Practice News Schneider, Mary Ellen January 15, 2007 700+ words
...surveys. Trends in red blood cell folate levels from the 1999-2000 through 2003...becoming pregnant consume 400 mcg of folic acid daily to reduce the chance of neural...reason behind the reported drop in folate levels is unknown, but the researchers...
- Folate levels in young American women fall, could lead to rise in birth defects.
- News wire article from: The America's Intelligence Wire January 4, 2007 700+ words
...fortified with folic acid to help prevent...were succeeding: Folate levels increased, and...clear why blood folate levels dropped in this...women need more folic acid to prevent neural...amount than the folic acid in enriched breads...in the drop in ...
- Folate Levels in the Evalution of Macrocytosis or Anemia.
- Magazine article from: Internal Medicine Alert Kuritzky, Louis March 29, 2001 700+ words
...intake. Even though RBC folate levels better represent body...retrospectively reviewing all folate levels (n = 2998) ordered...only half of subnormal folate levels were so-indicated...clinicians actually received folic acid replacement therapy...
- Serum folate levels jumped among women aged 15-44. (From 1988 to 2000).(Brief...
- Magazine article from: Family Practice News Tucker, Miriam E. October 15, 2002 700+ words
Median serum folate levels in women of childbearing age nearly...Examination Survey (NHANES). Serum folate levels were lowest in black women in 1999...consume 400 [micro]g(0.4 mg) of folic acid per day to reduce the risk of having...
- Serum folate levels tripled between 1988 and 2000. (Women Aged 15-44 Years).
- Magazine article from: OB GYN News Tucker, Miriam E. October 15, 2002 700+ words
Median serum folate levels in women of childbearing age nearly...Examination Survey (NHANES). Serum folate levels were lowest in black women in 1999...consume 400 [micro]g (0.4 mg) of folic acid per day to reduce the risk of having...
- Preventing and detecting neural tube defects.(optimizing folate levels)
- Magazine article from: Medical Laboratory Observer Miller, Sharon M. May 1, 1999 700+ words
...this objective is to optimize folate levels. Background Along with 2...call for consumption of more folic acid than was established in 1989...years to spread the word that folic acid can greatly reduce the risk...adequate consumption of folic acid offers a convenient, ...
- Mothers' folate levels linked to birth weight.(Obstetrics)
- Magazine article from: OB GYN News Mahoney, Diana September 1, 2005 700+ words
...birth weight. Each standard deviation increase in maternal folic acid level was associated with a 14% weight increase in birth...maternal folate status are not independent of each other. Folate levels were significantly lower in women who smoked than in nonsmokers...
- Tomatoes engineered to provide high folate levels.(BIOTECHNOLOGY)
- Newspaper article from: Food Chemical News Clapp, Stephen March 19, 2007 700+ words
...and Canada require all grain products to be fortified with folic acid, the synthetic form of folate. "However, food fortification...standard serving, they said, adding: "To our knowledge, the folate levels we achieved are the highest reported for plants; our tomatoes...
Source: HighBeam Research, New clinical trial research research has been reported by J....