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Recent findings from Safdarjung Hospital highlight research in trachoma prevention.
Current study results from the report, 'Potential of a novel polyherbal formulation BASANT for prevention of Chlamydia trachomatis infection,' have been published. "The effect of a novel polyherbal formulation BASANT on Chlamydia trachomatis was studied. In vitro sensitivity testing was done by direct exposure of C. trachomatis (pre-infection incubation with BASANT) and exposure of C. trachomatis within HeLa 229 cells (post-infection incubation with BASANT)," scientists in New Delhi, India report (see also Trachoma Prevention).
"Pre-infection incubation of standard serovar D/UW-3/Cx with BASANT showed complete inhibition after 60, 30 and 15 min of incubation at concentrations of 12, 30 and 60 microg/mL, respectively. In the post-infection incubation, 8-10 microg/mL of BASANT showed complete inhibition of standard serovar D/UW-3/Cx as well as of five clinical isolates of C. trachomatis after 48 h of incubation. BASANT also inhibited a clinical isolate obtained from a doxycycline treatment failure patient at a concentration of 30 microg/mL," wrote A.R. Bhengraj and colleagues, Safdarjung Hospital.
The researchers concluded: "Both assays with standard and clinical isolates showed that BASANT has antimicrobial activity ...
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