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Researchers from University Hospital report on findings in drug resistance.(Report)
According to recent research published in the Journal of Antimicrobial Chemotherapy, "An increase in antibiotic resistance of Escherichia coli, the most common pathogen in urinary tract infections (UTIs), is encountered worldwide. Optimal treatment of UTIs will contribute substantially to limit antibiotic use and antimicrobial resistance."
"This study determined trends in antimicrobial resistance of uropathogenic E. coli, which can be of use to optimize UTI guidelines. During 1998-2005, E. coli from urine samples of patients attending urology services were collected in three regions in The Netherlands: north-east (NE, n = 1084), west (W, n = 1064) and south (S, n = 1212). The antibiotic susceptibility was determined using microbroth dilution following CLSI guidelines. E. coli ATCC 35218 and ATCC 25922 were used as reference strains. Amoxicillin resistance remained stable over time (37% to 47%), but was higher in the south (44%) compared with the other regions (40%; P
The researchers concluded: "National and regional surveillance of antibiotic resistance is important to keep therapeutic guidelines up-to-date and adequate for the treatment of resistant microorganisms."
Nys and colleagues published their study in the Journal of Antimicrobial Chemotherapy (Trends in antimicrobial susceptibility of Escherichia coli isolates from urology services in The Netherlands (1998-2005). Journal of Antimicrobial Chemotherapy, 2008;62(1):126-132).
For additional information, contact S. Nys, University Hospital Maastricht, Dept. of Med Microbiology, Maastricht, Netherlands.
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Source: HighBeam Research, Researchers from University Hospital report on findings in drug...