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Data on birth weight discussed by researchers at University of London.

Women's Health Weekly

| August 07, 2008 | COPYRIGHT 2008 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

In this recent report, researchers in London, the United Kingdom conducted a study "To compare adult lung function in two national British cohorts, born in 1946 and 1958, in relation to birth weight, postnatal growth and early air-pollution exposure. Persons born in U.K., Scotland and Wales during 1 week in March 1946 and in 1958 and followed from childhood into adult life."

"Forced expiratory volume in 1 sec (FEV1) and forced vital capacity (FVC), measured at age 43 years on subjects born in 1946 (n = 2167) and age 44-45 years on subjects born in 1958 (n = 5947). Spirometric indices were adjusted for gender, adult standing height, smoking history and socioeconomic position in childhood, and analysed in relation to birth weight, growth pattern and area of birth, classified into four groups of differing exposure to domestic coal smoke pollution. Within each cohort, FEV1 and FVC were positively associated with birth weight and proportional sitting height independent of adult height. Pooling results for both cohorts, the mutually adjusted increment in FEV1 per 1SD increment was 30 ml (95% CI 16 to 45) for birth weight and 19 ml (95% CI 5 to 33) for proportional sitting height. The proportion of adult height attained by age 7 years and early air-pollution exposure were unrelated to adult lung function," ...

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