AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Reports summarize arthritis study results from University of Gothenburg, Sahlgrenska Academy.(Report)
According to a study from Gothenburg, Sweden, "Both oestrogen deficiency and the inflammatory disease contribute to the generalized bone loss seen in postmenopausal rheumatoid arthritis (RA). Oestradiol and the selective oestrogen receptor modulator raloxifene have been shown to ameliorate the disease in collagen-induced arthritis (CIA), a well-established animal model for human RA."
"The aim of this study was to investigate whether raloxifene-treatment would be beneficial in long-term treatment of established CIA, both regarding anti-arthritic and anti-osteoporotic properties. Female dilute brown agouti mice were ovariectomized and CIA was induced. Raloxifene or vehicle treatment was administered 5 days per week, and the clinical arthritis score was evaluated continuously. At termination, bone mineral density was analysed, paws were collected for histological examination and sera were analysed for markers of bone and cartilage turnover, as well as antibodies to type II collagen and levels of interleukin (IL)-6. Treatment with raloxifene is beneficial in long-term treatment of established CIA. It hampers the disease severity and frequency, protects the joints from destruction and protects against the development of osteoporosis. The proinflammatory cytokine IL-6 was down-regulated in raloxifene-treated mice compared with controls. The serum levels of antibodies to collagen were not affected by raloxifene-treatment," wrote C. Jochems and colleagues, University of Gothenburg, Sahlgrenska Academy (see also Arthritis).
The researchers concluded: "Long-term treatment with ...
- Gambro Finances Professorship in Nephrology At the Sahlgrenska Academy.
- Press release article from: Business Wire April 3, 2002 700+ words
...professorship in nephrology at the Sahlgrenska Academy at Goteborg University in Sweden...over the world, among them the Sahlgrenska Academy. The goal is to always be in the...cooperation in renal care with the Sahlgrenska Academy. For many years Sweden has played...
- Investigators at Gothenburg University, Sahlgrenska Academy publish new data on...
- Newspaper article from: Blood Weekly March 26, 2009 700+ words
...colleagues, Gothenburg University, Sahlgrenska Academy. The researchers concluded...Laboratory Cardiovascular Research, Sahlgrenska Academy, S-41345 Gothenburg, Sweden...Engineering, Gothenburg University, Sahlgrenska Academy. This article was prepared by Blood...
- Studies from University of Gothenburg, Sahlgrenska Academy yield new...
- Newspaper article from: Gastroenterology Week June 15, 2009 700+ words
...colleagues, University of Gothenburg, Sahlgrenska Academy. The researchers concluded...Microbiology & Immunology, Sahlgrenska Academy, Box 435, SE-40530 Gothenburg...Disease, University of Gothenburg, Sahlgrenska Academy. This article was prepared by Gastroenterology...
- Investigators at University of Gothenburg, Sahlgrenska Academy release new data...
- Newspaper article from: Life Science Weekly June 16, 2009 700+ words
...colleagues, University of Gothenburg, Sahlgrenska Academy (see also Life Sciences). The...Lundgren, University of Gothenburg, Sahlgrenska Academy, Institute Health & Care...Sciences, University of Gothenburg, Sahlgrenska Academy. This article was prepared by Life...
- New data from Gothenburg University, Sahlgrenska Academy illuminate research in...
- Newspaper article from: Obesity & Diabetes Week May 18, 2009 700+ words
...colleagues, Gothenburg University, Sahlgrenska Academy. The researchers concluded...Kindblom, Gothenburg University, Sahlgrenska Academy, Institute Medical, Center Bone...Osteoporosis, Gothenburg University, Sahlgrenska Academy. This article was prepared by Obesity...
- Findings from University of Gothenburg, Sahlgrenska Academy provide new...
- Newspaper article from: Biotech Week April 29, 2009 700+ words
...colleagues, University of Gothenburg, Sahlgrenska Academy (see also Life Sciences). The...Ringstrom, University of Gothenburg, Sahlgrenska Academy, Institute Medical, Dept. of...Life, University of Gothenburg, Sahlgrenska Academy. This article was prepared by Biotech...
- Findings from University of Gothenburg, Sahlgrenska Academy advance knowledge...
- Newspaper article from: Blood Weekly April 23, 2009 700+ words
...colleagues, University of Gothenburg, Sahlgrenska Academy (see also Bone Research). The...Goransson, University of Gothenburg, Sahlgrenska Academy, Dept. of Biomaterials, Institute...Surgery, University of Gothenburg, Sahlgrenska Academy. This article was prepared by Blood...
- Scientists at University of Gothenburg, Sahlgrenska Academy describe research...
- Newspaper article from: Obesity & Diabetes Week February 2, 2009 700+ words
...colleagues, University of Gothenburg, Sahlgrenska Academy (see also Obesity and Diabetes...Chen, University of Gothenburg, Sahlgrenska Academy, Dept. of Molecular & Clinic...Mellitus, University of Gothenburg, Sahlgrenska Academy. This article was prepared by Obesity...
- Research data from University of Gothenburg, Sahlgrenska Academy update...
- Newspaper article from: Biotech Week April 29, 2009 700+ words
...colleagues, University of Gothenburg, Sahlgrenska Academy. The researchers concluded...Rheumatol & Inflammat Research, Sahlgrenska Academy, Guldhedsgatan 10, S-41346 Gothenburg...Inflammation, University of Gothenburg, Sahlgrenska Academy. This article was prepared by Biotech...
- New bone research reported from Gothenburg University, Sahlgrenska Academy.
- Newspaper article from: Biotech Week July 1, 2009 700+ words
...colleagues, Gothenburg University, Sahlgrenska Academy. The researchers concluded...amp; Maxillofacial Surgery, Sahlgrenska Academy, Box 450, S-41390 Gothenburg...Treatment, Gothenburg University, Sahlgrenska Academy. This article was prepared by Biotech...
Source: HighBeam Research, Reports summarize arthritis study results from University of...