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"The diagnosis of nongenital Neisseria gonorrhoeae infection by the Becton Dickinson ProbeTec ET Chlamydia trachomatis and N. gonorrhoeae Amplified DNA assay had low positive predictive value among an Australian community-based sample of homosexual men," investigators in Australia report (see also Gonorrhea).
"Only 30.4% of oropharyngeal samples and 73.7% of anorectal samples were positive for N. gonorrhoeae by the porA assay," wrote L.P. Mcnally and colleagues, St. Vincent's Hospital.
The researchers concluded: "The accuracy of nucleic acid amplification tests in this context is compromised without supplemental testing."
Mcnally and colleagues published their study in Clinical Infectious Diseases (Low positive predictive value of a nucleic acid amplification test for ...
Source: HighBeam Research, Study results from St. Vincent's Hospital update understanding of...