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No need for gene screens in breast cancer families.
Research reported should provide relief to women who are worried after a relative's breast cancer diagnosis. The study in the open access journal BMC Cancer shows that a family history of breast cancer does not give a useful indication of the likelihood that a woman will develop it herself at an early age (see also BioMed Central).
An increased risk of breast cancer for relatives of breast cancer patients has been demonstrated in many studies. As physicians and the general population have become more aware of this increased risk, the demand for referring healthy women with a family history of breast cancer for intensive screening or genetic testing has risen. Geertruida H. de Bock led a team from Leiden University Medical Centre in the Netherlands who investigated whether the increased risk was significant enough to accurately predict breast cancer.
According to de Bock, "Due to the low prevalence of early breast cancer in the population, the predictive value of a family history of breast cancer was 13% before the age of ...
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...7; 3.0 to 4.6) breast cancer Family history of 38.1 (1.8...3; 2.6 to 4.2) breast cancer Family history of 283 (1.4; 1...4 to 0.6) 6.60 breast cancer Family history of 98 (0.5; 0...
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- Magazine article from: Women's Health Weekly April 17, 2003 700+ words
...with noncarriers. A family history of breast cancer can be an indication...of 99) had a strong family history of breast cancer and/or ovarian cancer...of women without a family history of breast cancer. "Our findings underline...
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...diagnosis of bilateral breast cancer came at age 50 or later. In women without a family history of breast cancer before age 50 or ovarian...women with bilateral breast cancer before age 50 but a negative family history was not significantly...
- Management of women with a family history of breast cancer in the North West...
- Magazine article from: Journal of Medical Genetics McAllister, M. O'Malley, K. Hopwood, P. Kerr, B. Howell, A. Evans, D. G. R. July 1, 2002 700+ words
...not implicated, a family history of breast cancer increases a woman...referrals per year for a family history of breast cancer. However, when...increased risk for breast cancer because of their family history to a dedicated Family...
- A Truncated BRCA1 Gene Mutation Identified in a Hispanic-American Breast Cancer...
- Magazine article from: Medicine of the Americas Shen, Dejun Wu, Yanyuan Chillar, Ram Vadgama, Jaydutt V. September 1, 2000 700+ words
...patient was diagnosed with breast cancer at age 51 and has a family history of breast cancer. To the best of our...cancer or early-onset breast cancer. Recent population...that neither age nor family history can independently predict...
- Breast Cancer Legacy: Your Family History, Your Future.(Audiovisual Review)
- Magazine article from: Library Journal Hagloch, Susan B. June 1, 2005 700+ words
Breast Cancer Legacy: Your Family History, Your Future. color. 50 min. Beth Murphy, Principle Pictures...and including their's. Testing is now able to pinpoint breast cancer indicator genes, although having such a gene does not necessarily...
- Advice about mammography for a young woman with a family history of breast...
- Magazine article from: British Medical Journal Lucassen, Anneke Watson, Eila Eccles, Diana April 28, 2001 700+ words
...women under 50 with a family history of breast cancer The sensitivity and...women under 50 with a family history of breast cancer, although such screening...management women with family history breast cancer." This gave 50 hits...
- Review: breast cancer is associated with a family history of the disease in...
- Magazine article from: Evidence-Based Nursing July 1, 2002 700+ words
QUESTION: In women with a family history of breast cancer, how does the pattern of breast...industrialised countries, almost 90% of breast cancer patients do not have a family history of breast cancer, and that for women with only 1...
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- Magazine article from: Women's Health Weekly December 19, 2002 700+ words
...NewsRx.net) -- A family history of breast cancer does not increase a...whether women who had a family history of breast cancer were more likely to...endometrial cancer, but a family history of breast cancer had no bearing on this...
- Family history of breast cancer does not increase risk.(Brief Article)
- Newspaper article from: Cancer Weekly December 17, 2002 700+ words
...NewsRx.net) -- A family history of breast cancer does not increase a...whether women who had a family history of breast cancer were more likely to...endometrial cancer, but a family history of breast cancer had no bearing on this...
Source: HighBeam Research, No need for gene screens in breast cancer families.