Research from V. Vettriselvi and co-researchers yields new findings on obstetrics.

In this recent report published in the Journal of Obstetrics and Gynaecology Research, researchers in Chennai, India conducted a study "To assess the association between polymorphisms in angiotensin converting enzyme and methylene tetrahydrofolate reductase genes and recurrent pregnancy loss by a case-control study in South Indian women. DNA was extracted from peripheral blood leukocytes of 104 women with Recurrent Pregnancy Loss (RPL) and 120 controls."

"Genotyping of ACE Insertion Deletion and MTHFR C677T polymorphism were carried out by PCR and PCR-RFLP, respectively. No statistically significant difference was observed in the distribution of genotypes between cases and controls for ACE and MTHFR polymorphisms. Further, the combination of MTHFR and ACE genotypes failed to reveal an association. In conclusion, the present study reveals lack of association of MTHFR C677T and ACE I/D polymorphisms in RPL in South Indian women," wrote V. Vettriselvi and colleagues (see also Obstetrics).

The researchers concluded: "However, we cannot exclude the ...