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The role of cholesterol as a possible treatment for autism spectrum disorders (ASDs) is reviewed in the April issue of the International Review of Psychiatry. Essential for neuroactive steroid production, cholesterol also plays an important role in the growth of myelin membranes, and normal development of the embryo and fetus. Cholesterol deficits may contribute to ASDs, such as Smith-Lemli-Optiz syndrome (SLOS) which can result in abnormal enzyme functions. SLOS is characterized by a wide range of phenotypic …