Beakers To The Rescue.(Special Report)(biopharming)

Byline: Mac Margolis; With George Wehrfritz In Manila, Christopher Werth In London And Akiko Kashiwagi In Tokyo

Scientists say a new green revolution could head off future food crises.

Pity the papaya. odd-shaped and orange-fleshed, it lacks the iconic status of the apple or the stage presence of the banana. Lately, though, it has become something of an agronomic superstar. Last month a team of international researchers led by the University of Hawaii finished mapping the genome of a variety of papaya engineered to withstand ringspot virus. Ringspot is a killer; it nearly wiped out Hawaii's $17 million-a-year papaya industry. Then, in the late '90s, scientists came to the rescue by plucking a gene from the virus itself and splicing it into the papaya plant, like a vaccine. Today, Hawaii's papaya groves are flourishing and, with the genome in hand, scientists now believe they will be able to replicate similar harvest-saving technology for different crops around the world. Chalk one up for the second green revolution: the triumph of gene splicing.

When high-tech agriculture first hit the headlines, back in the 1960s and 1970s, it was all about applying conventional farming techniques in innovative ways: precision irrigation, chemical fertilizers and intensive crossbreeding to create high- yielding varieties of maize, rice and wheat for hungry nations like India, Latin America and Southeast Asia. Modern biotech got its liftoff in the 1980s, when a team of U.S. scientists discovered how to isolate genes from the DNA of one life form and then insert them into the cells of another. The green revolution became the gene revolution, and it has yielded a whole new suite of supercrops, from vitamin-packed corn to rice programmed for droughts. Some, such as a transgenic potato that requires just one eighth of the water of a normal spud, are still on the drawing board in test plots. Others, like golden rice, which comes bundled with an extra dose of vitamin A (the lack of which causes blindness around the world), are waiting to hit the supermarket, but have to pass muster with the health bureaucrats. According to industry analysts, biotech crops have already expanded from practically nothing a decade ago to 282 million hectares in 23 countries in 2007. The market for GM seeds has more than doubled since 2001, from $3 billion to $7 billion, says Gautam Sirur, head of Cropnosis, a U.K.-based agricultural consultancy. Although no one is projecting miracle yields, biotech enthusiasts say that once such products are unleashed on the marketplace, farmers will be able to grow more nutritious food at lower costs using less water and pesticides, and even in the most punishing weather.

The problem is that the second green revolution is encountering resistance more fierce than the first one ever saw. In key markets like France, Italy, Germany, Spain and Poland, most genetically modified fruits, vegetables and grains are still taboo. Environmental militants trample them in the fields. A mere trace of them in the cargo holds is enough for port authorities to turn away entire shiploads. According to a recent poll, two thirds of Europeans still disapprove of GM goods, even when they are cheaper than conventional or organic foods and require no chemical pesticides.

...