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Lyme disease season is quickly approaching. The standard treatment for Lyme disease is either oral or intravenous antibiotics. But nearly 60 percent of people who don't get antibiotics early in the illness develop intermittent or persistent arthritis. In addition, a small percentage of people with Lyme disease who do receive antibiotics have persistent arthritis for months or even several years. This has been called antibiotic-refractory, or slowly resolving, Lyme arthritis. Now, research in the December 2007 issue of Arthritis & Rheumatism shows that these lingering arthritis symptoms in people who have ...