Anti-CD8+ response seen in long-term survivors. (of HIV infection)

A significant anti-HIV CD8(+) lymphocyte response is seen in many HIV infected nonprogressors and asymptomatic long-term survivors when infected CD4(+) cells and autologous CD8(+) cells are cocultured, according to the results of a study from the University of California, Los Angeles (UCLA).

The findings, reported by John Ferbas and colleagues in the August 1995 issue of Journal of Infectious Diseases, are similar to those reported earlier in 1995 by Cao et al. (N Engl J Med, 1995;332:201-208).

"Our findings emphasize the need for further immunologic and virologic investigations of long-term survivors of HIV infection," Ferbas et al. wrote ("Virus Burden in …