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Registrar: MRCGP exam update - Aspirin as primary prevention.
Current situation
- Many healthy people over the age of 50 years in the UK regularly take aspirin.
- Patients at high risk of cardiovascular disease (CVD) are still not taking aspirin.
- The balance of risks versus benefits of aspirin for the prevention of CVD has not been established in the elderly.
What is the evidence?
- It has been estimated that 90-95 per cent of the population could take low-dosage aspirin without undesirable effects (BMJ 2005; 330: 1,440-1).
- An observational study in two UK hospitals showed that aspirin was the causal agent in 18 per cent of admissions for adverse drug reactions (BMJ 2004; 329: …
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