In vitro response to HIV envelope seen. (in person infected with HIV for long time without progressing to AIDS)

Sera from a woman who has been HIV positive since 1981 but has not progressed to AIDS had an absence of recoverable infectious virus and a strong in vitro proliferative response to HIV envelope proteins.

"Cohorts of long-term survivors and uninfected, persistently high-risk individuals suggest that the balance between disease versus effective immunity or infection versus resistance, respectively, may not be far from the equilibrium point in these groups of HIV-infected or exposed individuals," researcher David Schwartz and colleagues wrote ("Absence of Recoverable Infectious Virus and Unique Immune Responses in an Asymptomatic HIV+ Long-Term Survivor," AIDS Research and …