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A Giant Among Minnows: Giant Danio Can Keep Growing.
Byline: Staff Writers
MILWAUKEE, Dec. 5 (SPX) -- Two fish that share much in common genetically appear to have markedly different abilities to grow, a finding that could provide a new way to research such disparate areas as muscle wasting disease and fish farming, a new study shows.
The study in the November issue of the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, finds that the giant danio, unlike its cousin the zebrafish, appears to have the ability to recruit new muscle throughout its life. Humans have the same ability before birth, but mostly lose it after birth.
Because the zebrafish and giant danio are closely related, and the zebrafish's genome has already been mapped, scientists hope they can more easily identify the genetic keys to the difference in growth potential between them. According to co-author Peggy R. Biga, "I don't think there will be a major…
- Giant danio, zebrafish growth rate studied.
- News wire article from: UPI NewsTrack November 27, 2006 700+ words
...muscle wasting disease and fish farming. Researchers found the giant danio, unlike its cousin the zebrafish, appears to have the ability...but mostly lose it after birth. Because the zebrafish and giant danio are closely related, and the zebrafish's genome has already...
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- Magazine article from: American Zoologist EL HAJ, ALICIA J. June 1, 1999 700+ words
...some general conclusions regarding muscle growth and the factors which regulate this...Histological studies identify the stages of muscle growth in the leg and the abdomen Fibre length...These studies have demonstrated that muscle growth occurs by addition of new sarcomeres...
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...big, low-fat hindquarters may teach us something about muscle growth and fat metabolism, say researchers who found a gene involved...mutated, the gene inhibits fat cells and diverts energy into muscle growth, Dr. Jirtle told Indications. In humans, he added, a...
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- Magazine article from: Family Practice News Berger, Joanne M. October 15, 2002 700+ words
...big, low-fat hindquarters may teach us something about muscle growth and fat metabolism, say researchers who found a gene involved...mutated, the gene inhibits fat cells and diverts energy into muscle growth, he told Indications. In humans, he added, a similar...
- Muscle growth agent blocks myostatin, and more.(News: From The Lab)(Brief...
- Newspaper article from: BioWorld Week January 2, 2006 700+ words
...colleagues decided to see whether a broader-spectrum inhibition of myostatin would be even more effective in stimulating muscle growth. The scientists constructed a soluble form of the activin type 2B receptor, which normally binds myostatin in cell membranes...
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- Newspaper article from: Heart Disease Weekly July 5, 2009 700+ words
Knockout of myostatin, a growth factor that limits muscle growth, can decrease body fat and promote resistance against developing atherosclerosis, or "hardening" of the arteries, according...
- Defects in molecular trigger for muscle growth are important genetic cause.
- Newspaper article from: Heart Disease Weekly January 26, 2003 700+ words
...of California, San Diego (UCSD) School of Medicine have determined the molecular machinery that triggers normal cardiac muscle growth and survival, and have linked defects in this complex to an inherited form of human cardiomyopathy, a type of heart failure...
- New 'Mighty Mice' Research Brings Muscle Growth Closer To Reality.
- Newspaper article from: Genomics & Genetics Weekly August 17, 2001 700+ words
...the other two groups, one with excess mutant activin II receptors and one with myostatin peptide, also showed increased muscle growth. Scientists are hopeful that the finding will provide new opportunities to treat many muscle-wasting diseases like muscular...
- Doctor nears breakthrough in muscle growth research.
- News wire article from: Europe Intelligence Wire June 24, 2009 700+ words
...tissue and blood samples he has taken from them. He said: "I'm looking for the optimum amount of exercise and nutrition to stimulate muscle growth. When I started it felt like a very high mountain to climb and now I'm almost there."
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