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Byline: Christopher Rowland
Nov. 16--A set of articles to be published today in the New England Journal of Medicine is spurring new scrutiny of the use of antianemia drugs to boost red blood cell counts beyond Food and Drug Administration recommendations.
The FDA said yesterday it will review new data from one of the studies, called CHOIR, which was halted before its completion last year. A safety panel stopped the trial after patients with chronic kidney disease receiving larger doses of Johnson & Johnson's drug Procrit to increase red blood cell counts began dying at an unexpectedly high rate.
FDA officials said they want to see whether they can solve a puzzle: At what point does aggressive anemia treatment increase risk?
"Now we have a new piece,…