Phenotype of alveolar versus blood T lymphocytes in the acquired immunodeficiency syndrome and modulation of markers of activation by alveolar macrophages. (Research Report)

AUTHORS: R.A. Abbud, S.L. Alt and E.A. Rich. University Hospitals of Cleveland, Cleveland, Ohio.

According to an abstract submitted by the authors to a joint meeting of the American Federation for Clinical Research, to be held April 29 - May 2, 1994, in Baltimore, Maryland, "Patients with the acquired immunodeficiency syndrome (AIDS) often have a CD8 predominant lymphocytic alveolitis and markers of activation (MOA) are frequently expressed on alveolar lymphocytes (AL). This study addresses the relationship between blood lymphocytes (BL) and AL and modulation of MOA on lymphocytes by alveolar macrophages (AM). Bronchoalveolar cells (BAC) were obtained from …