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A new study found significant improvement in cognitive functions in healthy older adults following 6 months of treatment with growth hormone releasing hormone (GHRH). According to the investigators, this is the first clear evidence that GHRH treatment improves cognitive performance in healthy older men and women, and may also hold promise as potential treatment for individuals with mild cognitive impairment (MCI) or Alzheimer's disease (AD).
Age-related declines in a number of physiological functions, including cognition, are thought to be associated with declines in activity of the somatotrophic axis. Hormonal supplementation, for example with growth hormone (GH) and insulin-like growth factor I (IGF-I), has been reported to arrest or partially reverse such changes.
Cognitive deficits have been observed in GH-deficient adults as well as in GH-deficient …