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Cardiovascular experts have warned GPs to avoid NSAIDs in patients with heart failure after a study of UK general practice found they increased the risk of hospitalisation with the disease.
Researchers found NSAIDs increased the risk of a first hospitalisation with heart failure by 30 per cent - a risk they said, although small, `could have a considerable public health impact'.
Patients with a prior diagnosis of heart failure were at a 7.3-fold increased risk of a hospitalisation compared with those without the disease, and this rose to a 8.6-fold increase in patients on NSAIDs.
Study leader Dr Consuelo Huerta, a researcher at the Spanish Centre for…