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NSAIDs should only be used in elderly patients as a last resort because they increase heart failure risk by a third, experts say.
Prescribers are currently advised by the MHRA always to use NSAIDs at the lowest effective dose, for the shortest time necessary to control symptoms.
But an analysis of the General Practice Research Database has shown that even using NSAIDs for a short duration at a low dose increases the risk of admission to hospital with heart failure in people over 60 years old.
The study included 1,396 patients, aged 60-84 years, who had been hospitalised for heart failure in 1997-2000, and 5,000 controls of the same age. Overall, 11…