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Investigational renin blocker may reduce end-organ damage.(Cardiovascular Medicine)
Atlanta -- Treatment with aliskiren, a drug from a new class of antihypertensire agents, led to safe and effective blood pressure lowering in a phase III study with 672 patients.
"Aliskiren has the potential to be an important new treatment for hypertension, with placebolike tolerability and sustained, 24-hour action," Dr. Byung-Hee Oh said at the annual meeting of the American College of Cardiology.
But what some experts find even more compelling is the potential aliskiren might have for preventing end-organ damage, such as heart failure, because it works by blocking renin, the rate-limiting enzyme for the entire renin-angiotensin-aldosterone system (RAAS). …
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