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Itopride for functional dyspepsia.(CLINICAL CAPSULES)(Brief article)(Clinical report)
For patients with functional dyspepsia, treatment with itopride for 8 weeks provides a significantly greater reduction in symptoms than does placebo, according to results from a recent randomized trial.
Itopride is a dopamine D2 antagonist that inhibits acetylcholinesterase activity. In Japan, the drug is often prescribed for functional dyspepsia, even though it had not been evaluated in randomized, controlled trials.
In the current study, Dr. Gerald Holtmann of the University of Adelaide (Australia) and his associates randomized 554 patients with functional dyspepsia to receive itopride at 50 mg, ...
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