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Rx for heart failure-related apnea.(acetazolamide for central sleep apnea)(Brief article)
A 6-day course of acetazolamide appeared to improve sleep-disordered breathing in a study of 12 men with heart failure-related central sleep apnea.
In central sleep apnea (CSA), respiration temporarily ceases because of a decline in partial pressure of carbon dioxide (PC[O.sub.2]) below the apneic threshold. However, in a randomized, double-blind study by Dr. Shahrokh Javaheri and his associates, the diuretic and respiratory stimulant acetazolamide seemed to reduce the likelihood of PC[O.sub.2] crossing the apneic threshold by inducing a state of metabolic acidosis. Dr. Javaheri of the University of Cincinnati and associates evaluated acetazolamide in 12 men with stable heart failure with left ventricular systolic dysfunction and CSA (Am. J. Respir. Crit. Care Med. 2006;173:234-7).
For 6 nights, patients received either placebo or a single dose (3.5 mg/kg) of acetazolamide and 30 mEq of potassium chloride (to offset the urinary potassium loss ...
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- Magazine article from: FOCUS: Journal for Respiratory Care & Sleep Medicine Grenard, Steven November 1, 2008 700+ words
...therapy to prevent obstructive sleep apnea. [ILLUSTRATION OMITTED] An important property of central sleep apnea is that it spontaneously starts...used the term "complex" sleep apnea to lump central sleep apneas and other CPAP and...
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- Magazine article from: FOCUS: Journal for Respiratory Care & Sleep Medicine Linley, Laura June 22, 2004 700+ words
...sleep. Not to be overlooked is Central Sleep Apnea Syndrome; characterized by...with oxygen desaturation. Central Sleep Apnea is a respiratory disturbance...patients can experience apnea. Central sleep apnea may be triggered by erratic...
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- Magazine article from: Clinical Psychiatry News Finn, Robert June 1, 2009 700+ words
SAN FRANCISCO -- Patients exhibiting central sleep apnea are three times more likely to have an anxiety disorder...sleep clinic shows. There was no association between central sleep apnea (CSA) and depression or between obstructive sleep...
- central sleep apnea
- Reference information from: The Mosby Medical Encyclopedia October 1, 1996 700+ words
The Mosby Medical Encyclopedia 10-01-1996 central sleep apnea, a condition in which a person stops breathing during sleep because of reduced output from the central nervous system. It may...
- Association Between Sleep Apnea and Death Points to Need to Examine Treatments,...
- News wire article from: Ascribe Higher Education News Service November 9, 2005 700+ words
...CPAP) for patients with central sleep apnea and heart failure, was led...editorial, Dr. Somers notes that central sleep apnea is characterized by intermittent...with both heart failure and central sleep apnea received either CPAP -- a...
- Percutaneous coronary intervention can improve sleep apnea.
- Newspaper article from: Heart Disease Weekly April 11, 2004 700+ words
...Percutaneous coronary intervention can improve sleep apnea. "Central sleep apnea is often recognized in patients with heart failure...reported "a chronic heart failure patient with central sleep apnea whose nocturnal desaturation was improved by...
- Methadone used for pain linked to sleep apnea: the sleep-disordered breathing...
- Magazine article from: Clinical Psychiatry News MacNeil, Jane Salodof January 1, 2007 700+ words
...approved for the treatment of central sleep apnea, mixed sleep apnea, and periodic...obstructive sleep apnea, 12% with central sleep apnea, and 21% with mixed obstructive and central sleep apnea. One-third of the patients...
- Sleep apnea may not be closely linked to heart failure severity.
- Newspaper article from: NewsRx Health & Science May 24, 2009 700+ words
Obstructive sleep apnea (OSA) and central sleep apnea (CSA) are not markedly decreased in heart failure...The study, "Prevalence and Physiological Predictors of Sleep Apnea in Patients with Heart Failure and Systolic Dysfunction...
