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Stress and the lonely rat: Study hints at why women cope better.

Chicago Tribune (Chicago, IL)

| February 27, 2006 | COPYRIGHT 2007 Chicago Tribune. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Byline: Peter Gorner

Feb. 27--Female rodents handle stress much better than males, which may hint at why women seem better able to survive social isolation than men, a pioneering University of Chicago research team reported Monday.

The difference in the female lab rats' responses may stem from the demands of motherhood, the researchers speculated. The idea is that mothers who can fend off stress and injury can better protect their young.

The study used 120 rats to document the long-lasting effect that three months of isolation and one 30-minute episode of acute physical stress had on the function of the rodents' immune systems.

The researchers measured what is known as the inflammatory response, the body's initial, fundamental immune reaction to bacteria, viruses and other invaders.

Just two…

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