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Scientists who studied Vioxx deny ethics breach.
Byline: Stephen Smith
Feb. 23--Scientists who conducted a pivotal study of the blockbuster painkiller Vioxx yesterday insisted that they violated no ethical obligations by failing to include in a medical journal report all information about heart problems suffered by patients in the clinical trial.
The researchers were responding to a stinging rebuke issued in December by The New England Journal of Medicine, which in 2000 had published the study of Vioxx, a pill trumpeted by its maker, Merck & Co., as providing pain relief without the stomach bleeding caused by other drugs. Merck, the journal wrote in December, had failed to notify editors about some patients' cardiovascular complications though at least two of the authors learned of them while the manuscript was being reviewed.
The journal editors requested that the researchers correct their earlier study, saying the omission resulted in the paper…
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