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BUSINESS BRIEFS.(TO THE POINT)

Investor's Business Daily

| February 03, 2006 | COPYRIGHT 2006 Investor's Business Daily, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

MEDICAL

Botox adds wrinkle to earnings

Allergan, perhaps best known for its Botox wrinkle cream, said Q4 earnings rose to 91 cents per share ex items, 2 cents above views. Revenue rose 7% to $595 mil, but sales growth for Botox fell shy of expectations. 2006 earnings are forecast at $3.56-$3.62 per share, excluding stock-option expenses. Shares fell 1.5% to 113.09.

Doubts cloud AstraZeneca outlook

England's second-biggest drug maker said Q4 earnings rose 40% to 77 cents a share, 2 cents over views. Revenue climbed 8% to $6.28 bil, largely due to sales of its ulcer treatment Nexium and anti-psychotic Seroquel. AstraZeneca forecast '06 earnings of $3.40-$3.60 a share, topping views of $3.27. But that outlook includes 45 cents a share tied to the heart drug Toprol-XL. Genetic firms have won a ruling striking down Toprol's patent protection. Shares fell 4.5% to 46.80.

** Ista Pharmaceuticals surged 11% to 7.97 after it said a late-stage study of an eye treatment was effective in reducing eye inflammation in patients at risk of a bacterial ...

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