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Severe liver injury with atomoxetine.(CASE REPORT)(Brief Article)

The Brown University Child and Adolescent Psychopharmacology Update

| December 01, 2005 | (Hide copyright information)Copyright

The authors of this case report utilized a computerized search of databases (Eli Lilly and Co.) to review the hepatobiliary safety of atomoxetine (Strattera) during clinical trials and in the first 2 years after its approval. Although a number of potential liver injury cases were identified, they write that only two spontaneously reported cases appeared "probably related" to atomoxetine therapy. In one case a 31-year-old woman developed acute hepatitis after taking atomoxetine 40 mg/day for 2.5 months. The other is summarized here:

 
    Patient: Male, 14 y.o. 
    Medications: atomoxetine (Strattera), sertraline (Zoloft)

Comment: A 14-year-old boy with …

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