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The Gene Hunter; Thomas Hudson: His lab is homing in on the precise causes of specific diseases.(Cover Story)
Byline: Mary Carmichael
To call Dr. Tom Hudson modest would be putting it, well, modestly. One of the world's premier investigators of genetically linked disease, he discovered four years ago that DNA is inherited in chunks--the principle at the heart of the HapMap, the recently completed project describing millions of variations in the human genome. Yet Hudson, 44, an associate professor of medicine and human genetics at McGill University in Canada, says: "I was just the biologist on the team. I'm not the person who decided you need .1 microns here and .5 there." He'll admit only to having "a knack for engineering and gadgets."
Hudson is much more voluble on the subject of the Human Genome Project, the 13-year effort to identify more than 20,000 genes in the human DNA lineup, which he helped make happen. If you're wondering why the project hasn't produced enough drugs to stock your cabinet yet, he says, never fear: combined with information from the HapMap and tools like the ones his lab is developing now, it's about to start yielding results. "I wanted to find genes for common diseases back in 1991, when I originally joined the Human Genome Project," he says. "But I realized quickly that the tools didn't exist. If you wanted to find a gene for colon cancer and you didn't ...
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- Encyclopedia entry from: UXL Encyclopedia of Science January 1, 2002 700+ words
Human Genome Project The Human Genome Project is the scientific research effort to construct a complete...fifteen-year project, and on October 1, 1990, the Human Genome Project officially began. It was to be coordinated with the existing...
