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Alnylam will take shot at the flu.

The Boston Globe (Boston, MA)

| December 15, 2005 | This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Byline: Stephen Heuser

Dec. 15--Alnylam Pharmaceuticals Inc., a Cambridge biotechnology company, said it will start development next year on a treatment for pandemic flu, funded partly by a grant from the US Department of Defense.

The treatment would use a new technique, RNA interference, in which short strands of genetic material are custom-built to shut down flu virus genes.

The company has developed several possible RNAi drugs that have stopped flu viruses from reproducing themselves in a test tube, chief executive John Maraganore said yesterday, and plans to apply to start human testing on one or two substances in the second half of 2006.…

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