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Ex-Merck scientist's views on Vioxx changed.(Dr. Edward Scolnick)

Houston Chronicle (Houston, TX)

| December 06, 2005 | Belli, Anne | COPYRIGHT 2007 Houston Chronicle. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Byline: Anne Belli

Dec. 6--The former top scientist at Merck testified Monday that he initially concluded an internal study of Vioxx linked the drug to an increase in heart attacks and strokes less than a year after it was approved for sale.

In a videotaped deposition shown to a Houston jury, Dr. Edward Scolnick, the president of Merck Research Labs until 2002, acknowledged writing a company e-mail in which he noted that the cardiovascular links to Vioxx were "clearly there."

He said he changed his opinion just 18 days later after reviewing other data and literature, joining company officials in their position that there was no such link. Still, the cardiovascular issue continued to bother him even after Merck's marketing department put out a press release reaffirming the…

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