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WASHINGTON -- More than half of North American women receiving treatment for osteoporosis have suboptimal serum vitamin D levels, Anne E. de Papp, M.D., and her associates reported in a poster at the annual meeting of the American Association of Clinical Endocrinologists.
Inadequate vitamin D concentrations can lead to alterations in calcium and phosphate homeostasis, secondary hypoparathyroidism, bone loss, osteoporosis, and an increased risk of fractures.
Yet, data from a cross-sectional study of 1,536 postmenopausal women at 61 North American sites suggest the problem is often overlooked in osteoporosis patients, said Dr. de Papp, of Merck & Co. Inc., West Point, Pa., and her associates.
"We advocate the use of vitamin D supplementation and patient counseling regarding the importance of vitamin D in all women with osteoporosis," they said in the poster.
The patients had a mean age of 71 years (range, 47-103 years) and a mean body mass index (BMI) of 26.4 kg/[m.sup.2]. A total of 92% were Caucasian and 35% resided at latitude greater than or equal to ...