Registrar: MRCCP Exam update - C-reactive protein and CHD.(coronary heart disease)

Current situation

- It is well known that C-reactive protein (CRP) is a sensitive marker of inflammation.

- Elevated CRP levels are usually accompanied by high cholesterol levels and high levels of other traditional CHD risk factors.

- A high CRP level is significantly more common in association with obesity, overweight, and diabetes (Arch Intern Med 2005; 165: 2,063).

PCRP is increasingly being recommended as a screening test for CHD.

What is the evidence?

- One study showed that middle-aged men without cardiovascular disease (CVD) who had raised CRP levels were more likely to die from a cardiovascular cause than those …