Interleukin-4 receptor (IL-4R) expression on AIDS-related Kaposi's sarcoma (AIDS-KS) cells and inhibition of tumor cell growth and cytokine production by IL-4. (Research Report)

AUTHORS: P. Gill and R.K. Puri. Department of Medicine, University of Southern California, Los Angeles, California; and Division of Cytokine Biology, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Bethesda, Maryland.

According to an abstract presented to the Eighty -Fourth Annual Meeting of the American Association for Cancer Research, held May 19-22, 1993, in Orlando, Florida, "We have previously demonstrated that a variety of human solid tumors express high affinity IL-4R and IL -4 can inhibit growth of these cells in vitro. In the present study, we have examined a) the expression of IL -4R on AIDS-KS derived spindle cells at …