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Researchers remake 1918 flu, look for answers to avian flu.
Byline: Jeremy Manier
CHICAGO _ Government researchers have remade the deadly "Spanish flu" virus responsible for the 1918 global outbreak that killed up to 50 million people, a resurrection they hope will reveal weaknesses of the modern bird flu strains that threaten a new pandemic.
Although the work carries some risk if the virus were to escape from the lab, many experts believe the bug would be less devastating now because people have acquired natural immunity to related strains.
Working under high security at the federal Centers for Disease Control and Prevention in Atlanta, scientists identified many of the genes and proteins that made the old strain lethal, and rebuilt the virus. Mice infected with it died within five days.
The team also concluded that the virus leaped directly to humans from a source in birds _ unlike lesser pandemics in 1957 and 1968 in which viruses from animals and humans swapped genes.
Reports on their work Wednesday in the journals Science and Nature come amid signs of increased…
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Source: HighBeam Research, Researchers remake 1918 flu, look for answers to avian flu.
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