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Is HIV infection associated with an increase in the prevalence of cervical neoplasia? (Periodical Report)
SOURCE: British Journal of Obstetrics and Gynaecology, February 1993;100(2):149-153.
The risk of cervical intraepithelial neoplasia (CIN) in women with HIV infection is increased only in individuals with immunosuppression, a British study indicates.
Charing Cross and Westminster Medical School researcher J.R. Smith and colleagues set out to test three hypotheses: that HIV infection predisposes to CIN; that CIN is a result of HIV-related immunosuppression; and that CIN is a result of immunosuppression causing increased expression of the potentially oncogenic viruses human papilloma virus (HPV), Epstein Barr virus (EBV) and herpes simplex virus (HSV). …
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