AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.

Perospirone * may improve food refusal.(Case Report)

The Brown University Geriatric Psychopharmacology Update

| July 01, 2005 | COPYRIGHT 2005 Wiley Periodicals, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Patient: 5 patients (ages 59-80 years; 4 female, 1 male) Medications: Perospirone

Comment: Perospirone was administered to 5 patients (4 are presented below) with psychiatric disorders who refused food. They were given no other concomitant antipsychotic agent; minimal doses of hypnotic drugs were given to the patients only when they complained of insomnia.

Patient 1: Female, 80 y/o, diagnosed with delusional disorder, exhibited food refusal and hostile behavior. She developed akathisia during haloperidol therapy. During perospirone monotherapy, her refusal of food and her hostility decreased. No extrapyramidal-symptom-related complaints or akathisia were reported. Maintenance monotherapy with perospirone (16 mg/twice daily) resulted in improvements in her condition.

Patient 2: Male, 68 y/o, presented with hypochondriacal delusions of colon cancer, depressive mood, reduced energy and severe food refusal. Computerized tomography scan and intestinal fiberoscopy results were normal. Initial laboratory tests showed he was dehydrated. He received risperidone oral solution 2 mg/day for 10 days without improvement in symptoms. Risperidone was then tapered and perospirone was started and titrated up to 24 mg/day. Complete improvement was seen in food refusal at this dose and he appeared cheerful with no depressive symptoms.

Patient 3: Female, 68 y/o, presented with delusions of persecution, aggressiveness, auditory hallucinations and food refusal. She had consumed alcohol heavily for 40 years and had memory impairment. She gradually stopped eating 3 weeks before admission. ...

Related articles from newspapers, magazines, journals, and more
Two subtypes of food refusal in preteens found.(Child/Adolescent Psychiatry)
Magazine article from: Clinical Psychiatry News Brunk, Doug December 1, 2005 700+ words
...age children who present with severe food refusal, Robyn S. Mehlenbeck, Ph.D...aged 6-12 years, who presented with food refusal and restrictive eating habits to a day...anorexia." Identifying children with food refusal problems early "may help quite a bit...
Food Refusal.
Newspaper article from: Pediatrics for Parents March 1, 1999 700+ words
...straightforward and not a cause for concern. The most common causes of food refusal include irregular meal times, putting too much food on the...and using food for inappropriate bargaining. Rarely is food refusal a reflection of lingering fear after a choking episode...
Research by G. Okugawa and colleagues in schizophrenia provides new insights.
Newspaper article from: Biotech Week July 1, 2009 700+ words
"Perospirone is classified as a second-generation...for the treatment of schizophrenia. Perospirone binds with high affinity to serotonin...no reports of clinical comparisons of perospirone and risperidone in multicenter studies...
Studies from Nanjing Medical University yield new information about...
Newspaper article from: Biotech Week September 3, 2008 700+ words
...and validated for the determination of perospirone in human plasma, using quetiapine as...study the pharmacokinetic parameters of perospirone hydrochloride tablets in healthy Chinese...study in Chromatographia (Estimation of perospirone in human plasma by LC-MS-MS and...
J&J Files NDA for New Formulation for Risperdal.(Johnson and Johnson's Janssen...
Magazine article from: Chemical Market Reporter Krause, Carey September 10, 2001 700+ words
...998 1,123 Quetiapine 106 79 Risperidone 841 812 Ziprasidone 248 412 Zotepine 17 16 Other antipsychotics * 392 338 Total 2,853 3,035 (*)Includes sales of Blonanserin, Iloperidone, Perospirone Source: Decision Resources Inc.
Maurice goes on hunger strike in prison protest.
Newspaper article from: South Wales Echo (Cardiff, Wales) August 5, 2009 700+ words
...said yesterday: "A prisoner at HMP Cardiff is refusing food. "Guidance to prison staff on managing food refusal states that food refusal should always be taken seriously." South Wales Police declined to comment, saying the matter is now...
An assessment of the potential of Family Day Care as a nutrition promotion...
Magazine article from: Nutrition & Dietetics: The Journal of the Dietitians Association of Australia Daniels, Lynne A. Franco, Bunny McWhinnie, Julie-Anne March 1, 2003 700+ words
...percent of respondents reported non-neutral approaches to food refusal and dawdling (reward, punishment, cajoling) that overrode...strengthening skills in the management of common problems, such as food refusal and dawdling, consistent with the current evidence for approaches...
Simple strategies to end those "I don't want to eat" blues.
Newspaper article from: Pediatrics for Parents Mianecki, Therese July 1, 2008 700+ words
...Some examples include food fussiness, mealtime negativity, food refusal, perseverant feeding, fussy eating, picky eating, selective...neophobia. One of the most common problems that parents face is food refusal, with most pre-school children refusing to eat certain...
For more facts and information, see all results
©2009 Gale, a part of Cengage Learning. All rights reserved.
About us | FAQs | Contact us | Privacy policy | Terms and conditions
Other Gale sites: Encyclopedia.com | HighBeam Research | Acquire Content | Books & Authors | Goliath | MovieRetriever | Smart QandA