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Insomnia Drug Helps Depressives Have Sweet Dreams; New Data Offer Hope; Combo of Lunesta with antidepressants helps both ailments, firm says.(HEALTH & MEDICINE)
Byline: AMY REEVES
Most people who've suffered bouts of depression or anxiety can tell you: It's never worse than at 3 in the morning.
Sleep trouble is a common symptom of mood disorders like depression. For Sepracor, maker of the new insomnia drug Lunesta, that signals an opportunity.
Last month Sepracor presented data from new studies that combined Lunesta with fluoxetine, better known as Prozac. The 10-week studies, each with a few hundred patients, found improved sleep and hinted Lunesta might help with the underlying depression.
The positive results have implications for Sepracor as well as the herd of similar drugs coming down the pipe from Neurocrine Biosciences, Sanofi-Aventis, Japan's Takeda and Merck.
Sepracor Chief Financial Officer David Southwell spoke to IBD about what the studies found.
IBD: What motivated you to conduct these studies?
- Comorbid insomnia/depression responds to cotherapy.(Psychiatry)
- Magazine article from: Internal Medicine News Jancin, Bruce September 1, 2005 700+ words
...Societies. Comorbid insomnia is common in patients with major depression. This study shows...reluctant to treat insomnia associated with major depression using a hypnotic...Patients with primary insomnia who later developed depression were ineligible...
- Sepracor Announces Publication of Additional Data from Lunesta(R)...
- Press release article from: Business Wire February 21, 2007 700+ words
...adverse events, rebound insomnia or rebound depression, and improvements in sleep...Published Results From the Insomnia-Depression Study The results of the...placebo-controlled insomnia-depression study of LUNESTA were published...
- Comorbid insomnia-depression may respond to cotherapy.(Adult Psychiatry)
- Magazine article from: Clinical Psychiatry News Jancin, Bruce September 1, 2005 700+ words
...Societies. Comorbid insomnia is extremely...patients with major depression. The main achievement...reluctant to treat insomnia associated with major depression using a hypnotic...with primary insomnia who later developed depression were ineligible...
- Genetic link found between anxiety, depression and insomnia.
- Newspaper article from: NewsRx Health June 28, 2009 700+ words
...Significant genetic effects shared between insomnia, depression and anxiety suggests that overlapping...III-R criteria was used to assess insomnia, depression and anxiety. Criteria for insomnia were met by 19.5 percent of the sample...
- Sepracor Announces Publication of LUNESTA(TM) Insomnia-Depression Study in...
- Press release article from: Business Wire April 4, 2006 700+ words
...criteria for both insomnia and MDD (either...scores (Hamilton Depression Rating Scale...fewer symptoms of depression). Other key secondary...was no rebound insomnia upon discontinuation...severity of their depression at various time...After removing insomnia-specific questions...
- Insomnia, depression can haunt quitters.
- Newspaper article from: Knight Ridder/Tribune News Service Krasner, Steven April 9, 1999 700+ words
...a much publicized bout with insomnia and depression as he tried to kick his 13...year, but his recovery from depression cost him much of the season...cold turkey led to his clinical depression. ``You ask 10 doctors and...
- Clinical Trials Update: July 15, 2009; Frequent Nighttime Urination (Nocturia)...
- News wire article from: Consumer Health News (English) July 15, 2009 700+ words
...CatID=576. ----- Insomnia If you are an adult who has...CatID=189. ----- Depression If you take medication for depression but still have symptoms...clinical_trials/condition/depression.aspx. ----- Atherosclerotic...
- 'Since he's gone, I don't laugh anymore': heart palpitations. Insomnia....
- Magazine article from: O, The Oprah Magazine Kogan, Deborah Copaken June 1, 2007 700+ words
...I don't laugh anymore': heart palpitations. Insomnia. Depression. Though far from the battlefields, the families...experienced combat in Iraq exhibited symptoms of major depression, serious anxiety, or post-traumatic stress disorder...
