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Couples accept prenatal genetic testing with CMA: there was a 71% acceptance rate of chromosome microarray analysis in those undergoing amnio or CVS.(Obstetrics)
GRAPEVINE, TEX. -- Chromosome microarray analysis may play a vital role in the diagnosis of genetic disorders prenatally, Christine Eng, M.D., commented during a meeting that was sponsored by the American College of Medical Genetics.
Although chromosome microarray analysis (CMA) already has an established role in the genetic evaluation of both children and adults, its use still is being evaluated in the prenatal setting.
"This study represents the initial use of CMA in pregnancies being monitored due to increased risk of chromosomal abnormalities," said Dr. Eng of Baylor College of Medicine, Houston.
"It demonstrates a high level of acceptance and accuracy."
Dr. Eng and her associates discovered that there was a 71% acceptance rate of CMA among couples in which the woman was undergoing amniocentesis or chorionic villi sampling (CVS).
Reasons for acceptance of the CMA test included having a previous child with anomalies, an abnormal ultrasound finding, maternal age, and a desire to learn as much as possible about the current pregnancy.
Reasons for declining testing included the perception that the disorders being tested were rare and concern that the test results would raise anxiety.
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Source: HighBeam Research, Couples accept prenatal genetic testing with CMA: there was a 71%...