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GRAPEVINE, TEX. -- Researchers are attempting to develop a first-trimester cervical swab test to detect fetal genetic disorders.
While the test still is under development, if proven effective, it could provide noninvasive, earlier prenatal screening and possibly eliminate the need for amniocentesis and chorionic villi sampling (CVS).
"Early prenatal diagnosis to detect fetal genetic disorders is desired by both expectant mothers and physicians to make informed decisions," Farideh Z. Bischoff, Ph.D., of Baylor College of Medicine, Houston, said at a meeting sponsored by the American College of Medical Genetics.
"Current methods of prenatal testing carry a small but finite risk of miscarriage, and the results rarely are available before 12 to 16 weeks of pregnancy, due to the time required for cell culture," Dr. Bischoff said.
Recovery and analysis of fetal trophoblast cells would provide a safe alternative approach for rapid noninvasive prenatal diagnosis, she said.
The researchers are using micro electro mechanism system (MEMS) channels to ...
Source: HighBeam Research, Fetal genetic disorders test being developed.(Obstetrics)