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Interleukin-1 induces HIV-1 replication in a chronically infected promonocytic cell line (U1) via the IL-1 receptor type I, but not the IL-1 receptor type II. (Research Report)
AUTHORS: E.V. Granowitz, M.Z. Wang, C.A. Dinarello and P.R. Skolnik. Department of Medicine, New England Medical Center Hospitals and Tufts University School of Medicine, Boston, Massachusetts.
According to an abstract submitted by the authors to the American Federation for Clinical Research, American Society for Clinical Investigation, Association of American Physicians, Society for Investigative Dermatology and Society for General Internal Medicine Joint Meeting, held April 30 - May 3, 1993, in Washington, D.C., "We investigated the effects of IL-1 on HIV-1 p24 Ag (p24 Ag) production in the chronically infected promonocytic U1 cell line. IL-1alpha and IL -1beta …
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