Prenatal PAH exposure causes genetic changes in newborns.(Chromosomal Damage)

Research has suggested that in utero exposure to pollutants can cause DNA damage, chromosomal changes, and increased risk of childhood cancers such as leukemia. Other studies have indicated that pediatric leukemia is initiated prior to birth. Now NIEHS grantee Frederica Perera and colleagues at Columbia University demonstrate for the first time that prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) causes chromosomal changes that have been linked to leukemia and other cancers.

PAHs are a group of more than 100 different chemicals that are formed during the incomplete burning of almost any organic substance, including coal, oil, and gasoline. PAHs can cross …