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Renewed scrutiny for Vioxx, other COX-2 inhibitors.

Houston Chronicle (Houston, TX)

| February 16, 2005 | COPYRIGHT 2007 Houston Chronicle. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Byline: Leigh Hopper

Feb. 16--Heart bypass patients and people at risk for colon cancer were at increased danger of heart attacks or strokes when treated with Vioxx, Celebrex and Bextra, according to three new studies published Tuesday, offering further evidence of problems posed by drugs known as COX-2 inhibitors.

The studies -- two from Houston and one from Harvard -- were released early by the New England Journal of Medicine for public health reasons and to coincide with a three-day Food and Drug Administration meeting.

At the meeting, which starts today, physicians and scientists will try to find a balance between benefits and risks of COX-2 drugs, which are taken by millions of people.

"I think we are at risk of losing the class of drugs," said Dr. Robert Bresalier, a University of Texas M.D. Anderson Cancer Center researcher who led a study on the use of Vioxx in preventing cancer. "That's why…

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