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BUSINESS BRIEFS.(TO THE POINT)

Investor's Business Daily

| December 01, 2004 | COPYRIGHT 2004 Investor's Business Daily, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

MEDICAL

Icahn loses grip on Mylan Labs

Asset manager Richard Perry neutralized investor Carl Icahn's hostile takeover bid for the generic drug maker by becoming the No. 1 shareholder in Mylan Laboratories. Icahn made the $5.4 bil bid because he opposed Mylan's proposed $4 bil buyout of King Pharmaceuticals. Perry holds a 7 mil share stake in King. Perry Corp now owns 9.89% of Mylan, topping Icahn's 9.8%. King rose 7.5% to 12.45; Mylan fell 1% to 18.16.

Syneron Med drops on FDA move

The maker of cosmetic medical devices plunged 27% to 27.05 after the FDA rejected its application for its VelaSmooth cellulite-smoothing device. The FDA said Syneron Medical must reapply under a more stringent category. The Israeli company said it plans to ask for an investigational device exemption, which will let it use VelaSmooth in a clinical study to collect safety and effectiveness data.

Novartis pulls drug application

The drug firm is temporarily shelving a European Union application for its painkiller Prexige; it's delayed a U.S. filing several times. The drug is a cox-2 inhibitor, the same class of drugs as Merck's withdrawn Vioxx. EU authorities are reviewing cox-2 inhibitors for safety concerns. At one point, Prexige was thought to be a blockbuster with $2 bil annual sales. Novartis fell 2% to 48.05.

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