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HT attenuates increase in bone resorption marker associated with calciuric diet.

Women's Health Weekly

| December 02, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Postmenopausal hormone therapy use appears to attenuate the increase in a bone resorption marker associated with a calciuric diet, study data indicate.

Researchers in Ireland studied "the influence of a high-sodium, high-protein diet on bone metabolism in postmenopausal women (aged 49-60 years) stratified by hormone replacement therapy (HRT) use."

"In a crossover trial, 18 women [n=8 HRT users (+HRT) and n=10 nonusers (-HRT)] were randomly assigned to a diet high in protein (90 g/day) and sodium (180 mmol/day) (calciuric diet) or a diet moderate in protein (70 g/day) and low in sodium (65 mmol/day) for 4 weeks followed by crossover to alternative dietary regimen for a further 4 weeks," reported M. Harrington and colleagues, National University of Ireland.

Measurements revealed that "the calciuric diet significantly (p

"While the calciuric diet increased urinary N-telopeptide crosslinks of collagen (by about 25%, p=0.003) in the -HRT group, it had no effect in the +HRT group," Harrington and colleagues said.

"It appears that postmenopausal HRT use attenuates the ...

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