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2004 DEC 2 - (NewsRx.com & NewsRx.net) -- An update on work in the area of hormonal male contraception was provided at the 195th Meeting of the Society for Endocrinology, held November 1-3, 2004.
F. Wu, with the University of Manchester's Department of Medicine, explained, "Maintenance of spermatogenesis depends on adequate gonadotrophin and intratesticular testosterone concentrations. Hormonal contraception for men interrupts this physiological axis by various means of gonadotrophin suppression; this induces reversible azoospermia or severe oligozoospermia in virtually all men.
"Clinical trials have confirmed that high contraceptive efficacy, similar to female hormonal contraceptives, can be reliably attained with few side effects. However, the simultaneous suppression of Leydig cell steroidogenesis mandates the requirement ...