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Research and commercial interest in hormonal male contraception renewed.

Women's Health Weekly

| December 02, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 DEC 2 - (NewsRx.com & NewsRx.net) -- An update on work in the area of hormonal male contraception was provided at the 195th Meeting of the Society for Endocrinology, held November 1-3, 2004.

F. Wu, with the University of Manchester's Department of Medicine, explained, "Maintenance of spermatogenesis depends on adequate gonadotrophin and intratesticular testosterone concentrations. Hormonal contraception for men interrupts this physiological axis by various means of gonadotrophin suppression; this induces reversible azoospermia or severe oligozoospermia in virtually all men.

"Clinical trials have confirmed that high contraceptive efficacy, similar to female hormonal contraceptives, can be reliably attained with few side effects. However, the simultaneous suppression of Leydig cell steroidogenesis mandates the requirement ...

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